NIPT Requisitions

OHIP-Funded NIPT

Dynacare | Harmony Prenatal Test

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Download MOH Checklist

LifeLabs | Panorama NIPT

Download Requisition and MOH Checklist

All twin pregnancies are now eligible for OHIP-funded NIPT

Provincial NIPT Labs at a Glance

Factors to consider when choosing between the two provincial NIPT labs:

Singletons

Pregnancy Type	Questions to Consider	Harmony® Prenatal Test \| Dynacare	Panorama^TM NIPT \| LifeLabs
non-IVF singleton pregnancy	Can NIPT be done?	Yes	Yes
IVF singleton pregnancy	Can NIPT be done when a pregnant individual's own oocytes are used?	Yes	Yes
IVF singleton pregnancy	Can NIPT be done when a gestational carrier (surrogate) is involved?	Yes	Yes
IVF singleton pregnancy	Can NIPT be done when donor eggs (not self) are used?	Yes	Yes
Any singleton pregnancy	Can NIPT screen for sex chromosome aneuploidies?¹	Yes, and is available as an opt-in option	Yes, and is available as an opt-out option
Any singleton pregnancy	Can NIPT be done in a "vanishing" twin / co-twin demise scenario?²	No	No

¹ - Twin pregnancies generally cannot be screened for sex chromosome aneuploidies. However, PanoramaTM can screen for sex chromosome aneuploidies in monozygotic twin pregnancies only.

² - "Vanishing" twin pregnancy is a pregnancy that started as a twin pregnancy with subsequent loss of fetal heart activity or loss of the embryo in one of the pregnancy sacs.

Multiple Gestation (twins or more)

For most twin pregnancies, NIPT can be ordered through either LifeLabs or Dynacare. There are two types of IVF twin pregnancies that can only have NIPT through Dynacare: donor egg was used or a surrogate is involved.

Pregnancy Type	Questions to Consider	Harmony® Prenatal Test \| Dynacare	Panorama^TM NIPT \| LifeLabs
non-IVF twin pregnancy	Can NIPT be done?	Yes	Yes Zygosity testing is included (which means it can can tell you if the twins are identical or fraternal)¹
IVF twin pregnancy	Can NIPT be done when a pregnant individual's own oocytes are used?	Yes	Yes Zygosity testing is included
IVF twin pregnancy	Can NIPT be done when a gestational carrier (surrogate) is involved?	Yes	No (only singletons)
IVF twin pregnancy	Can NIPT be done when donor eggs (not self) are used?	Yes	No (only singletons)
Any pregnancy	Can NIPT be done for higher order multiples?	No	No

1 - Chorionicity, rather than zygosity, has an impact on the outcome of twin pregnancies. Zygosity testing can complement, but not replace, ultrasound evaluation of chorionicity in some clinical scenarios. For example, evaluating zygosity through NIPT may impact pregnancy surveillance when chronicity assignment is uncertain, and can help interpret “high risk” aneuploidy results.

Private-Pay NIPT

If none of the MOH criteria for OHIP-funded NIPT are met, a pregnant individual may choose to pay for private-pay NIPT, meaning that they can pay for this testing themselves or may get it covered through private health insurance.

Private-pay NIPT can be ordered through LifeLabs and Dynacare, as well as other commercial laboratories. Please note that different requisitions are needed for private-pay NIPT than for OHIP-funded NIPT, and these requisitions can be found on the labs' websites.

Prenatal Screening Ontario is unable to endorse any specific private-pay test or laboratory. On our website, we encourage you to read further about what factors you and the pregnant individual in your care may choose to consider when making decisions about private-pay tests.

Are you a health-care provider who would like to schedule a virtual education session about prenatal screening in Ontario?

Non-invasive Prenatal Testing (NIPT) Requisitions

OHIP-Funded NIPT

Provincial NIPT Labs at a Glance

Private-Pay NIPT

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